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Lamotrigine may cause severe or life-threatening skin rash, especially in children and in people who take too high...

Other non-stimulant ADHD medications include Kapvay (extended-release clonidine) and Intuniv (extended-release guanfacine). Kapvay and Intuniv are FDA-approved to treat ADHD in children and adolescents 6 to 17 years old. However, they have not been studied extensively in adults and are therefore not FDA-approved for adult ADHD treatment. However, a small placebo-controlled, double-blinded crossover study showed a possible benefit of using immediate-release guanfacine to treat ADHD in adults.Other than age, there are as yet no factors identified that are known to predict the risk of occurrence or the severity of rash caused by LAMICTAL. There are suggestions, yet to be proven, that the risk of rash may also be increased by (1) coadministration of LAMICTAL with valproate (includes valproic acid and divalproex sodium), (2) exceeding the recommended initial dose of LAMICTAL, or (3) exceeding the recommended dose escalation for LAMICTAL. However, cases have occurred in the absence of these factors.

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